Obesity a Key Risk Factor for off Springs with Diabetes Mellitus, of Type II Diabetic Parents

Abstract

Around the globe Type II diabetes is a major health issue that proceeds both from inheritance-environment interaction along with varied health risk factors like obesity and sedentary lifestyle. The body mass index (BMI) significantly linked diabetes to insulin resistance in people with high blood glucose levels. The main objective of this study was to determine a link between obesity and parental history (PH), which is a key risk factors for onset of Diabetes Mellitus (DM) in the offsprings of Type II diabetic parents. This study includes a total of 70 offsprings i.e. 50 obese and 20 non-obese offsprings from both genders with a familial history of diabetes (FHD). The important observations like BMI, Waist/Hip ratio, FBG test, 2hr OGTT and Urine examination were determined in control and test group individuals respectively. Thus, it is concluded that obesity and overweight are the key risk factor for onset of diabetes in offsprings as the mean of FBG was 115.5mg/dl as compared to 75.5mg/dl in controls and mean of 2-hr OGTT was 155.5mg/dl as compared to 89.9 mg/dl in controls respectively. However, cautious modifications in diet and exercises regime can aid to diminish or delay the onset of diabetes in offsprings with a prior history of Type II diabetic parents.