ANTIMICROBIAL SUSCEPTIBILITY BEHAVIOR OF BACTERIAL ISOLATES FROM DIFFERENT CLINICAL SAMPLES AT NISHTAR HOSPITAL MULTAN

Abstract

The pathogenic bacteria are getting resistant to antibiotics is significantly growing in the developing countries of the world including Pakistan. The present study was designed to find the basic study on resistance among the patients coming to the Nishtar Hospital, Multan. The study was carried out in the Department of Pathology, Nishtar Hospital, Multan. Total 387 clinical samples of urine, pus, high vaginal swab (HVS) and wound were surveyed for the existence of Gram-positive and Gram-negative pathogens. For these bacterial isolates, antimicrobial susceptibility tests were performed. E. coli was the most prevalent isolates followed by Staphylococcus aureus and Pseudomonas. E. coli was predominated in urine, pus, HVS and wound specimens. Occurance of Staphylococcus aureus, MRSA, Candida and Pseudomonas were 7.9 %, 3.9 %, 14.7 % and 1.4 % respectively among the clinical specimens. E. coli shows highest resistance to Linezolid (98.3%) followed by Ceftrizone (90.8%), Sulfamethoxazole + Trimethoprim (85%), Moxifloxacin (82.5%). High frequency of resistance specifies that there is an unremitting requirement of surveillance of resistance behaviour of antimicrobial agents in our study is to investigate the trend of this problem.